If you are talking about chemi-clean, I used it and it worked, didnt have any real problems, but every situation is different, so its up to you. Still, the slime is a byproduct of excess nutrients so getting the nitrates and phosphates down is really the best method and will produce the best long term results. There are more than a few different phosphate removal media available, some that can only be run for a couple of days, others that can be run long term. Also, controlling phosphates before they get into the tank is your best bet. Using only RO water and rinsing food before it goes into the tank will help alot. A uv sterilizer will have no effect on the slime.