IMO don't add any larger sizes deliberately. The finer the better. There will always be some large grains in any bag. Secondly, buy at least 20% more than you think you will need. I used 210 lbs in a 55g and ended up with 5" depth. I had to make a trip to the LFS in the middle of my changeover (for an extra 60 lbs) when it became apparent that the 150 lbs I planned on would only yield around 3". No matter where the large grains or pieces start, they will always end up on the top, where you do not really want them.