in the event of palytoxin poisoning
- Thread starter alix2.0
- Start date
wangotango
Active Member
Originally Posted by doc308
http:///forum/post/2924755
Several references on the net say there isn't any...
Tell your family goodbye.
I've heard a lot of stories about people getting really sick and tasting metal. If that's the case then I'd go to the hospital, but they usually have no idea what the hell palytoxin is.
-Justin
http:///forum/post/2924755
Several references on the net say there isn't any...
Tell your family goodbye.
I've heard a lot of stories about people getting really sick and tasting metal. If that's the case then I'd go to the hospital, but they usually have no idea what the hell palytoxin is.
-Justin
renogaw
Active Member
http://en.wikipedia.org/wiki/Palytoxin
Typical symptoms of palytoxin poisoning are angina-like chest pains, asthma-like breathing difficulties, tachycardia, unstable blood pressure, hemolysis (destruction of red blood cells), and an electrocardiogram showing an exaggerated T wave. The onset of symptoms is rapid, and death usually follows just minutes after.
Typical symptoms of palytoxin poisoning are angina-like chest pains, asthma-like breathing difficulties, tachycardia, unstable blood pressure, hemolysis (destruction of red blood cells), and an electrocardiogram showing an exaggerated T wave. The onset of symptoms is rapid, and death usually follows just minutes after.
florida joe
Well-Known Member
Palytoxin is a complex marine natural product containing 71 asymmetric centers. Palytoxin, isolated from soft coral, is considered to be one of the most toxic non-peptide substances known, second only to maitotoxin. Palytoxin was originally isolated in 1971 in Hawaii from the seaweed-like coral, "Limu make o hana (Seaweed of Death from Hana)"[1]. Later, in 1982 its full chemical structure was published by Prof. Daisuke Uemura and coworkers at Nagoya University[2][3][4]. Professor Yoshito Kishi's group at Harvard University first synthesized palytoxin in 1994[5][6]. This feat is still considered today by many to be the greatest synthetic accomplishment ever, due to its complexity in structure.
Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the molecule is locked in a position where it allows passive transport of both the sodium and potassium ions, thereby destroying the ion gradient that is essential for most cells.
Typical symptoms of palytoxin poisoning are angina-like chest pains, asthma-like breathing difficulties, tachycardia, unstable blood pressure, hemolysis (destruction of red blood cells), and an electrocardiogram showing an exaggerated T wave. The onset of symptoms is rapid, and death usually follows just minutes after.
Animal studies have shown that vasodilators, such as papverine and isosorbide nitrate, can be used as antidotes. The animal experiments only showed benefit if the antidotes were injected into the heart immediately following exposure.[7] Treatment in humans is symptomatic and supportive.
A case of human poisoning by palytoxin after contact with zoanthid corals (Parazoanthus sp.) in an aquarium through skin injuries on fingers is reported. The clinical symptoms include swelling, paraesthesia and numbness around the site of the injury spreading over the arm, but also signs of systemic poisoning such as dizziness, general weakness and myalgia, irregularities in the ECG and indications of rhabdomyolysis. Symptomatic treatment consisted of infusion of physiological fluids. The patient recovered within 3 days. Analysis of the zoanthid coral involved revealed extremely high concentrations of palytoxin (between 2 and 3 mg/g).
Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the molecule is locked in a position where it allows passive transport of both the sodium and potassium ions, thereby destroying the ion gradient that is essential for most cells.
Typical symptoms of palytoxin poisoning are angina-like chest pains, asthma-like breathing difficulties, tachycardia, unstable blood pressure, hemolysis (destruction of red blood cells), and an electrocardiogram showing an exaggerated T wave. The onset of symptoms is rapid, and death usually follows just minutes after.
Animal studies have shown that vasodilators, such as papverine and isosorbide nitrate, can be used as antidotes. The animal experiments only showed benefit if the antidotes were injected into the heart immediately following exposure.[7] Treatment in humans is symptomatic and supportive.
A case of human poisoning by palytoxin after contact with zoanthid corals (Parazoanthus sp.) in an aquarium through skin injuries on fingers is reported. The clinical symptoms include swelling, paraesthesia and numbness around the site of the injury spreading over the arm, but also signs of systemic poisoning such as dizziness, general weakness and myalgia, irregularities in the ECG and indications of rhabdomyolysis. Symptomatic treatment consisted of infusion of physiological fluids. The patient recovered within 3 days. Analysis of the zoanthid coral involved revealed extremely high concentrations of palytoxin (between 2 and 3 mg/g).
cleve_seahorse
Member
wear gloves , the big "shop" glasses to cover your eyes and keep pets....dogs,cats from the room and you should be ok....but have a cell phone near you "just in case"....that's one of THE most deadly toxins, and in ohio I'm not sure how much our doc's know about it
cleve_seahorse
Member
The shop glasses because I read that they can squirt when starting to frag....Don't want anything to happen
alix2.0
Active Member
i was just wondering because stephen pro came to our last club meeting and spoke about stuff in the aquarium that can kill you. he told us about how anthony calfo has poisoned himself with palytoxin three times. i figured that if anthony calfo can manage it once, let alone three times, it would probably be a good idea to know what to do in case i ever do. i mean, 911 is a given, but i wasnt sure if there was anything youre supposed to do in the meantime.
bang guy
Moderator
Originally Posted by 9supratt4
http:///forum/post/2924900
Just curious since I have these in my tank as well....how does someone get poisoned by them?? Is it from rubbing up on them? Or do you have to have an open wound? Or do they sting you? Or is it really only a concern while fragging?
I honestly do not believe palytoxin is the likely toxin. There are hundreds of other, more common, toxins that are much more likely to be encountered by hobbiests.
An open wound is the most common way toxins from a Zoanthid can enter the body. Foraminiferans can provide the wound when brushing a rock and any damage to a Paly or Zoa can provide the toxin.
http:///forum/post/2924900
Just curious since I have these in my tank as well....how does someone get poisoned by them?? Is it from rubbing up on them? Or do you have to have an open wound? Or do they sting you? Or is it really only a concern while fragging?
I honestly do not believe palytoxin is the likely toxin. There are hundreds of other, more common, toxins that are much more likely to be encountered by hobbiests.
An open wound is the most common way toxins from a Zoanthid can enter the body. Foraminiferans can provide the wound when brushing a rock and any damage to a Paly or Zoa can provide the toxin.