I am planning my 135 gallon reef, which I have now decided to up to a 180 gallon, and I'm going with 400 watt MH, because I want to keep SPS corals like acroporas and montiporas and euphorbias. I read in the "Sea-Scape" flyer (put out by Aquarium Systems) a couple of years ago that the 250 Watt MH's are not nearly as efficient as either 175 or 400 watt MH. That has really stuck in my mind. You could also go with just 2 400 watt if you want to keep some lower light stuff (like on the edges and maybe the middle depending on how you space the lights), and you'll only have to buy 2 fixtures instead of 3. Consider going to VHO actinic, since you can get 72 inch lamps, and one 72 inch lamp is 160 watts, like having 4 40 watt lamps. Just a thought.
Good luck,
Sonny