Hi, they say no, but I happen to have a clarki, and a perk together, but at first that big clarki tore into the perk, but now they get along. I wouldn't do it if I were you. They say you sometimes can do it if you have like a 220, and I only have a 55 gal. reef their in, and I really do think I lucked out. Clarki's are NASTY!! More than likely the clarki's will tear into the perk's not the other way, and you wouldn't want that. Good luck, and hope I helped, Ali:happyfish