Albion, many do use both. There are RO filters, DI filters, and RO/DI filters. RO has a great quantity of waste water from use. Expect to see 4:1 or 3:1 ratio of waste to good water. RO consists of a membrane that rejects a large percentage of elements, dissolved solids, and allows purer water through. DI has no waste water. DI does need to be regenerated or replaced often because once the capacity of the resins are reached, the resins do not filter any more. DI is probably cheaper in the beginning but the constant replacements of the resins may bring the total similar to RO or more. RO is more cost up front. What conditioners are you speaking of? What size is your tank? The amount of water needed will tell you what is better, cheaper, etc.