We have a 55 gallon tank at the office. We add it every monday right in the water. at home (150 gallons) I put it in the outgoing side of my sump. both have lr, fish & corals. hope this helps.
Rather then mess with individual supplements, I add Ecosystem's Reef Solution to the tank once a day. It adds strontium, molebdenum, and lots of other trace elements in the right amount. The corraline growth in this tank is incredible.