Unless you plan on taking everything out of the aquarium and draining it to drill it, I would say not to drill it...if you do want to drill it I would say you are gonna have to drain it to do it.
Unless you want to break the system down and then have it drilled. I think the sacrifice would be worth it in the long run. Talk to anybody with a hangon overflow and they will tell you how much they would rather have internals.