Not my work or words but thought it might help you. T712
Cupramine is a complex copper solution. Think of it as a buffered soln. The actual effective ppm is at ~0.25, but the total conc. is at 05.ppm. As I understand it, as the effective copper is used up/reduced, the "buffered" copper becomes active, thus maintaining the gradiant.
Two weeks is the "general" treatment for ******. Longer is better. For Amyloo, you definately need three weeks.
SeaChem recomends ramping up the Cupramine levels over three days or so. Treat at 0.25ppm (1ml/10 gal) for the first treatment, then add another dose of 1 ml/10gal to bring it up to 0.5 ppm on day 2 or 3.
In actuality, the copper is absorbed by many things, including calcium carbonate substrate (ie. live rock, dead coral, crushed gravel, and even detritius). It will take around 4 to 7 days for the copper levels to stabilize. Buy your self a good copper test kit that will indicate complex copper (not all do). Test the copper levels each day and add what is needed to bring the levels back up to 0.5 ppm (note to all: this is in regards to the use of Cupramine only).
If you have any questions, call SeaChem tech support and ask for Rusty.
Thomas