Remove visible bristles with tweezers. To remove tiny (often invisible) bristles, apply sticky tape to the area, then pull off gently. Regardless of technique, it's nearly impossible to remove all bristles. For persistent itching or skin rash, try 1 percent hydrocortisone ointment four times a day, and one or two 25 milligram diphenhydramine (Benadryl) tablets every 6 hours. These drugs are sold without prescription. Diphenhydramine may cause drowsiness. Don't drive, swim or surf after taking this medication.
No substance always relieves the pain and itching caused by these worms. Although unproven, home remedies of vinegar, rubbing alcohol, dilute ammonia, or a paste of meat tenderizer may help. If the sting is severe, or the area around any fireworm sting looks infected, see a doctor. An allergic reaction to fireworm venom is always a possibility. Go to an emergency room at the first sign of hives, a feeling of overall illness, or breathing difficulty.