I think it depends on your setup...IME, C. prolifera never went crazy on me. You can confine it to one spot in your tank and keep it pruned with little trouble (others such as C. racemosa and C. taxifolia and their variants will be much harder to control). Confining macro is even easier if you kind of separate the rockwork you grow it on from the rest of your rock...that way, whe it tries to "bridge" the gap, you can catch it more easily.
That being said, if you have a reef, you probably don't want it in the DT "just in case".
JM .02