Doubt the evidence is conclusive, just as running a UV would in some peoples opinion erradicate everything good........It's used to removed DOC, and wouldn't be detrimental......I've run ozone for over 4 years on a 150 with nothing but softies and had no issues.........IMO there are alot of bogus misinformation out there about stuff by people who haven't spent enought time with the item or can't really provide conclusive evidence to support their theory....