I actually removed my sand. My tank is about 100gal, so to minimize the shock to the fish I did it over three water changes (there is a lot of stuff in that sand, like nutrients and other things, which if suddenly removed might mess up the balance of the tank) .
First couple of times I took out as much of the sand as I could with the hose during the normal process of changing the water. Finally, on the third water change I removed enough water to fill two tupperware containers and I transfered all my fish and coral. Then I removed all the live rock and placed it in a third tupperware with water from the tank. I proceeded with removing ther remaining water and all of the sand. As I got to the bottom of the tank, I used rags to soak up the little sand left as there was not enough water left to use the hose anymore. Once done, I rearranged the rock, replaced most of the original water, plus added new water as I would during the normal water change, and finally reintroduced the coral and fish. It was a real success, and now the tank stays clean much longer.
Either way, the process should be the similar.
I was going to add back crushed rock and coral, but decided to leave it bare-glass bottom, in hope that over time coraline algae will take hold and make it really interesting - I've seen it done and it was amazing looking!
Once started, the final process was done with in about six hours, though my back hurt for about two days! Good luck!