I know alot of people who use fresh seawater and have no problems whatsoever. That being said, make sure you take it from an area that doesn't have alot of people traffic, don't take it near freshwater tribs, or anything that dumps stuff near there. Just use caution. Same with Live Sand....take it wading out where water is constantly hitting the sand. maybe even at least to where the water is at least 30 ft deep.....at least