scubadoo
Active Member
I've not tried and therefore cannot dismiss it as ineffective. Here is how it supposed to work....
How does it work?
Macrophages are a type of white blood cells that are found in most tissues and organs of the body. They play a central role in the defense of all multi-cellular animals against invading pathogens. Beta glucan is strongly stimulatory to macrophages (Seljelid et al., 1984). These white bloods cells, in turn, set in motion a cascade of other immune system activities. Macrophages circulate the body in search of foreign invaders (antigens).When they find a foreign invader they then engulf them through a process known as phagocytosis. They degrade the invader into peptides that are used to communicate the presence of foreign bodies to B-cells and T-Cells in the immune system. These cells are a part of the acquired immune system that learns to adapt and defend the body against specific threats. Simplified, acquired immunity is how the body becomes more resistant or immune to some pathogens after exposure.
Non-specific defense mechanisms of the immune system are vitally important in protecting fish (Secombs and Fletcher, 1992). Beta 1, 3 D glucan is a non-specific immune system stimulant, meaning that it activates the immune system to respond in a general way rather than against a specific type of pathogen or invader. This makes it a valuable tool against bacterial, viral, fungal and even parasitic pathogens, but it is not limited to these.
Beta glucan works as a biological defense modifier. It activates the immune system by stimulating receptors on macrophages that cause them to react as if a fungus is attacking the body. Biochemical studies have identified this receptor on fish macrophages and netrophils (Engstad and Robertsen 1993; Ainsworth 1994; Engstad and Robertsen 1994). Administering beta glucan begins a chain reaction of events which heighten cellular immune response. It stimulates the production of white blood cells such as macrophages, neutrophils and monocytes that combat invading pathogens. Cellular mobilization is increased helping immune system cells to recognize antigens and move to where they are needed most. The immune system's capacity to engulf non-self cells is augmented and the productions of anti-microbial agents are increased.
How does it work?
Macrophages are a type of white blood cells that are found in most tissues and organs of the body. They play a central role in the defense of all multi-cellular animals against invading pathogens. Beta glucan is strongly stimulatory to macrophages (Seljelid et al., 1984). These white bloods cells, in turn, set in motion a cascade of other immune system activities. Macrophages circulate the body in search of foreign invaders (antigens).When they find a foreign invader they then engulf them through a process known as phagocytosis. They degrade the invader into peptides that are used to communicate the presence of foreign bodies to B-cells and T-Cells in the immune system. These cells are a part of the acquired immune system that learns to adapt and defend the body against specific threats. Simplified, acquired immunity is how the body becomes more resistant or immune to some pathogens after exposure.
Non-specific defense mechanisms of the immune system are vitally important in protecting fish (Secombs and Fletcher, 1992). Beta 1, 3 D glucan is a non-specific immune system stimulant, meaning that it activates the immune system to respond in a general way rather than against a specific type of pathogen or invader. This makes it a valuable tool against bacterial, viral, fungal and even parasitic pathogens, but it is not limited to these.
Beta glucan works as a biological defense modifier. It activates the immune system by stimulating receptors on macrophages that cause them to react as if a fungus is attacking the body. Biochemical studies have identified this receptor on fish macrophages and netrophils (Engstad and Robertsen 1993; Ainsworth 1994; Engstad and Robertsen 1994). Administering beta glucan begins a chain reaction of events which heighten cellular immune response. It stimulates the production of white blood cells such as macrophages, neutrophils and monocytes that combat invading pathogens. Cellular mobilization is increased helping immune system cells to recognize antigens and move to where they are needed most. The immune system's capacity to engulf non-self cells is augmented and the productions of anti-microbial agents are increased.
! HTH, Leslie>