I can't recommend it. From what I've read over time they just produce more and more nitrates, so you'd probably be better off ditching 'em.
Bio-balls serve the same purpose as LR in the sense that they cultivate nitrifying bacteria. You really don't need bio-balls or LR rubble if you have plenty (1-2 lbs. per gallon) in the main tank. If you're a little on the low side, just switch out the balls for some rubble.