When I first decided to build an in-wall tank (before we even purchased this house), the idea was to have the tank built into a corner so that the front and one side pane would be visible. One of my reef club's members has his tank set up that way, and it's absolutely stunning.
But when my wife and I were deciding where to place the tank in this house, this space was the only one that made sense. The column basically renders that entire area of the room as wasted space so we figured it was the best place to set up the tank room. I still wanted to have two panes visible, so the front pane will be flush with the larger wall and the left side will basically be a window cut out in the wall so that the tank can still be viewed from multiple sides. Plus, I have a really large monti cap that I plan to place in front of that "window" that will provide an area for fish to hang out underneath; I anticipate this will become my Royal Grammas new home.