I had a large outbreak of ich in my 110 gal reef about 4 months ago, it killed my volitan lion, multicolor angel, powder blue tang, mandarin goby and had completely covered my adult purple tang (a long time resident) who was obviously dying like the others (respiratory problems, lying on the bottom, etc). I was pretty desperate, no way to remove the fish with all the live rock and the tank is loaded with hard and soft coral so conventional treatments were out of the question. I just figured that I was going to lose all of my fish, the only 2 left. I purchased a bottle of Kents garlic extreme, added it to the food and dosed the tank daily. The day after I started, there was a noticable decrease in parasites and the tang began to eat. By day 5 there were no visible parasites and the tang had quite an appetite. I kept up the regimen for 2 weeks and yes the skimmer and tank smelled like garlic. I have since repopulated the tank without problems, I did add a UV sterilizer to it. I'm a believer in garlic (and UV sterilizers). I wish that I had been open minded enough to use the garlic early on.