Puffers will likely nip at a star. I have a large CC star in my aggressive tank, every time his chips start to grow back the triggers take them off again. Triggers and alot of puffers will usauly take a test bite or two to make sure some is edible or not. With the bright red coloration, it is more likey to draw something in to take a test bite.
IMO I think that even the smaller puffers would still take a nip or two out of a general star.
HTH
-Brian