Just remember you have to do water changes on a grander scale. I have a 180 with a 50 gal fuge, 25 gal sump and 300 lbs of live rock. I only have 7 large fish in there but still must do a weekly 30 gallon water change to keep the nitrates down below 50ppm. 2 triggers, 1 puffer, 2 tangs, 1 large...