vasilithegreek, if you already have deco, rocks (LR or otherwise), substrate, etc in the tank, your tank volume is no longer 50 gallons. Chances are, it wasn't exactly 50 gallons to begin with, whether more or less, it was probably rounded.
It is easier to pre-mix the water in a seperate container and then add it to the tank versus trying to mix it in the tank. A bucket is easier to correct then a full tank. Also, mix lean and add to specs. After a couple of buckets, you will pretty much know how much salt you need.
I use a 32 gallon, new, trash can. I pre-measured and marked on exterior of can in 5 gallon increments. I fill it to the level I need, usually 25-30 gallons, add a slightly less then actually needed amount of salt. Let the air and a powerhead do the mixing and let it set for a couple of hours. The longer you can let it set the better. Gives the gasses involved a chance to equalize out. Then I pump it into the two tanks.